Entity Details

Primary name PPR3A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16821
EntryNamePPR3A_HUMAN
FullNameProtein phosphatase 1 regulatory subunit 3A
TaxID9606
Evidenceevidence at protein level
Length1122
SequenceStatuscomplete
DateCreated2004-09-13
DateModified2021-06-02

Ontological Relatives

GenesPPP1R3A

GO terms

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GOName
GO:0000164 protein phosphatase type 1 complex
GO:0005977 glycogen metabolic process
GO:0005979 regulation of glycogen biosynthetic process
GO:0008157 protein phosphatase 1 binding
GO:0016021 integral component of membrane
GO:2001069 glycogen binding

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR005036 CBM21 (carbohydrate binding type-21) domainDomainDomain
IPR038175 CBM21 domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
125853 OMIMDiabetes mellitus, non-insulin-dependent (NIDDM)A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. Disease susceptibility is associated with variants affecting the gene represented in this entry.