Entity Details

Primary name SOBP
Entity type gene
Source Source Link

Details

PrimaryID55084
RefseqGeneNG_028200
SymbolSOBP
Namesine oculis binding protein homolog
Chromosome6
Location6q21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSOBP_HUMAN

GO terms

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GOName
GO:0005634 nucleus
GO:0007605 sensory perception of sound
GO:0007626 locomotory behavior
GO:0032184 SUMO polymer binding
GO:0042472 inner ear morphogenesis
GO:0046872 metal ion binding
GO:0050890 cognition
GO:0090102 cochlea development

Diseases

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Disease IDSourceNameDescription
613671 OMIMMental retardation, anterior maxillary protrusion, and strabismus (MRAMS)A syndrome characterized by severe mental retardation, strabismus and dysmorphic features such as anterior maxillary protrusion with vertical maxillary excess, open bite and prominent crowded teeth. Some patients may lack dysmorphic features and manifest temporal lobe epilepsy and psychosis. Esotropia and amblyopia are present in some individuals. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
SOBPCELF3BioGRID, HPRD, IntAct16169070 details
SOBPCTBP1BioGRID, MINT21900206 details
SOBPSUMO2BioGRID23086935 29120074 details
SOBPHNRNPLBioGRID28611215 details
SOBPVIRMABioGRID29507755 details