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Entity Details
Primary name
NLRP2
Entity type
gene
Source
Source Link
Details
PrimaryID
55655
RefseqGene
NG_052633
Symbol
NLRP2
Name
NLR family pyrin domain containing 2
Chromosome
19
Location
19q13.42
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
2000-07-03
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
NALP2_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0005524
ATP binding
GO:0005737
cytoplasm
GO:0005794
Golgi apparatus
GO:0005829
cytosol
GO:0006915
apoptotic process
GO:0006954
inflammatory response
GO:0032088
negative regulation of NF-kappaB transcription factor activity
GO:0032090
Pyrin domain binding
GO:0032731
positive regulation of interleukin-1 beta production
GO:0043231
intracellular membrane-bounded organelle
GO:0043280
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087
innate immune response
Diseases
Show/Hide Table
Interactions
26 interactions
Interactor
Partner
Sources
Publications
Link
NLRP2
PYDC2
HPRD, UniProt
17178784
details
NLRP2
FAF1
BioGRID
17046979
details
NLRP2
APP
BioGRID
21832049
details
NLRP2
H2AX
MINT
15733840
details
NLRP2
WRN
MINT
15733840
details
NLRP2
SUGT1
BioGRID, DIP
17420470
17435760
details
NLRP2
MRE11
BioGRID
18285453
28345663
details
NLRP2
HSP90AA1
BioGRID
17435760
details
NLRP2
IKBKB
BioGRID
15456791
details
NLRP2
CHUK
BioGRID
15456791
details
NLRP2
IKBKG
BioGRID
15456791
details
NLRP2
PYCARD
BioGRID
15456791
details
NLRP2
RAD50
BioGRID
28345663
details
NLRP2
CARD8
HPRD
15030775
details
NLRP2
TTF1
BioGRID, IntAct
26496610
details
NLRP2
TAF13
BioGRID, IntAct
26496610
details
NLRP2
BCL7B
BioGRID, IntAct
26496610
details
NLRP2
TPP1
BioGRID, IntAct
26496610
details
NLRP2
CRIPT
BioGRID, IntAct
26496610
details
NLRP2
NLRP5
BioGRID, IntAct
26496610
details
NLRP2
GAPDH
BioGRID
26344197
details
NLRP2
LARP1
BioGRID
26344197
details
NLRP2
RBBP6
BioGRID
26496610
details
NLRP2
BECN1
BioGRID
26496610
details
NLRP2
CDH1
BioGRID
25468996
details
NLRP2
GSK3B
BioGRID
30711629
details
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