Entity Details

Primary name THSD1
Entity type gene
Source Source Link

Details

PrimaryID55901
RefseqGeneNG_047168
SymbolTHSD1
Namethrombospondin type 1 domain containing 1
Chromosome13
Location13q14.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTHSD1_HUMAN

GO terms

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GOName
GO:0005576 extracellular region
GO:0005768 endosome
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0048041 focal adhesion assembly
GO:0050840 extracellular matrix binding
GO:0071944 cell periphery

Diseases

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Disease IDSourceNameDescription
618734 OMIMAneurysm, intracranial berry, 12 (ANIB12)A form of cerebral aneurysm, a focal abnormal dilatation of a blood vessel in the brain. Berry intracranial aneurysms, also known as saccular aneurysms, have a characteristic rounded shape and account for the vast majority of intracranial aneurysms. They are the most common cause of non-traumatic subarachnoid hemorrhage, a sudden-onset disease that can lead to severe disability and death. Several risk factors such as smoking, hypertension, and excessive alcohol intake are associated with subarachnoid hemorrhage. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
THSD1GJA1BioGRID34079125 details
THSD1RAB11ABioGRID34079125 details