Entity Details

Primary name MAPK11
Entity type gene
Source Source Link

Details

PrimaryID5600
RefseqGeneNG_034042
SymbolMAPK11
Namemitogen-activated protein kinase 11
Chromosome22
Location22q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-08
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMK11_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001649 osteoblast differentiation
GO:0004674 protein serine/threonine kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007265 Ras protein signal transduction
GO:0010628 positive regulation of gene expression
GO:0032735 positive regulation of interleukin-12 production
GO:0035556 intracellular signal transduction
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0051149 positive regulation of muscle cell differentiation
GO:0051403 stress-activated MAPK cascade
GO:0060044 negative regulation of cardiac muscle cell proliferation
GO:0060348 bone development
GO:0071347 cellular response to interleukin-1
GO:0098586 cellular response to virus
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901796 regulation of signal transduction by p53 class mediator

Diseases

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Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
MAPK11TP53IntAct17254968 details
MAPK11ATF2BioGRID, HPRD, IntAct, MINT12761180 15304344 17254968 17380123 9235954 details
MAPK11ZNHIT1HPRD, MINT17380123 details
MAPK11MAPKAPK3BioGRID, IntAct21988832 23602568 26186194 28514442 details
MAPK11C9orf78BioGRID, MINT21900206 details
MAPK11CPNE6BioGRID, MINT21900206 details
MAPK11MAPK14BioGRID, IntAct, MINT21900206 23602568 details
MAPK11POLR3DBioGRID, MINT21900206 details
MAPK11SOCS3BioGRID, MINT21900206 details
MAPK11CRYAA2IntAct32814053 details
MAPK11CRYAAIntAct32814053 details
MAPK11DYNC1H1IntAct32814053 details
MAPK11DNM2IntAct32814053 details
MAPK11FGFR3IntAct32814053 details
MAPK11PAK1IntAct32814053 details
MAPK11PRKCAIntAct32814053 details
MAPK11KLK6IntAct32814053 details
MAPK11SMN1IntAct32814053 details
MAPK11SMN2IntAct32814053 details
MAPK11YWHAGIntAct32814053 details
MAPK11SETDB1IntAct32814053 details
MAPK11KAT5IntAct32814053 details
MAPK11GIPC1IntAct32814053 details
MAPK11LMO3IntAct32814053 details
MAPK11TARDBPIntAct32814053 details
MAPK11HDAC3BioGRID, HPRD15356147 details
MAPK11PMLBioGRID15273249 details
MAPK11CCND1BioGRID10952989 details
MAPK11MBPBioGRID, HPRD15728454 17906618 details
MAPK11HTRA2BioGRID17906618 details
MAPK11APPBioGRID21832049 details
MAPK11SH2D1ABioGRID9235954 details
MAPK11NOXA1BioGRID20110267 details
MAPK11MAPTBioGRID15632108 9199504 details
MAPK11PPM1DBioGRID28027003 details
MAPK11MAPKAPK2BioGRID, IntAct11551945 23602568 details
MAPK11TAB1BioGRID, HPRD, IntAct11847341 25241761 details
MAPK11PKN1BioGRID12761180 details
MAPK11GYS1BioGRID14680475 details
MAPK11EEF2KHPRD12171600 details
MAPK11MAPKAPK5HPRD9628874 details
MAPK11DUSP16HPRD11359773 details
MAPK11DUSP10HPRD11359773 details
MAPK11RPS6KA5HPRD9687510 details
MAPK11ELK1HPRD9235954 details
MAPK11ELK4HPRD9235954 details
MAPK11JUNHPRD9235954 details
MAPK11ESR2HPRD11579095 details
MAPK11BCL2HPRD11495898 details
MAPK11SP1IntAct14676314 details
MAPK11KRT1IntAct14676314 details
MAPK11MYBIntAct14676314 details
MAPK11MTREXIntAct14676314 details
MAPK11DUSP9BioGRID, IntAct23602568 27432908 27880917 28675297 details
MAPK11ARHGAP12BioGRID, IntAct23602568 details
MAPK11OBSL1BioGRID, IntAct23602568 details
MAPK11VARS1BioGRID, IntAct23602568 details
MAPK11CUL7BioGRID, IntAct23602568 details
MAPK11MKNK1BioGRID, IntAct23602568 details
MAPK11BAG3BioGRID23824909 details
MAPK11CCDC8BioGRID23602568 details
MAPK11HDAC1BioGRID26344197 details
MAPK11PPM1GBioGRID26344197 details
MAPK11DUSP2BioGRID27432908 details
MAPK11PTPN7BioGRID27432908 details
MAPK11PTPRRBioGRID27432908 details
MAPK11PTPN5BioGRID28675297 details