Entity Details

Primary name PTGDR
Entity type gene
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Details

PrimaryID5729
RefseqGeneNG_012118
SymbolPTGDR
Nameprostaglandin D2 receptor
Chromosome14
Location14q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPD2R_HUMAN

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004956 prostaglandin D receptor activity
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0016021 integral component of membrane
GO:0043303 mast cell degranulation

Diseases

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Disease IDSourceNameDescription
607277 OMIMAsthma-related traits 1 (ASRT1)Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis. Disease susceptibility is associated with variants affecting the gene represented in this entry.