Entity Details

Primary name CCL2
Entity type gene
Source Source Link

Details

PrimaryID6347
RefseqGeneNG_012123
SymbolCCL2
NameC-C motif chemokine ligand 2
Chromosome17
Location17q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-06-04
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsCCL2_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001525 angiogenesis
GO:0002548 monocyte chemotaxis
GO:0004672 protein kinase activity
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006468 protein phosphorylation
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006959 humoral immune response
GO:0007010 cytoskeleton organization
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0008009 chemokine activity
GO:0008360 regulation of cell shape
GO:0009617 response to bacterium
GO:0009887 animal organ morphogenesis
GO:0019079 viral genome replication
GO:0019221 cytokine-mediated signaling pathway
GO:0019233 sensory perception of pain
GO:0019725 cellular homeostasis
GO:0030593 neutrophil chemotaxis
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031727 CCR2 chemokine receptor binding
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035684 helper T cell extravasation
GO:0036499 PERK-mediated unfolded protein response
GO:0043491 protein kinase B signaling
GO:0043524 negative regulation of neuron apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0043615 astrocyte cell migration
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048246 macrophage chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0050870 positive regulation of T cell activation
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071222 cellular response to lipopolysaccharide
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071407 cellular response to organic cyclic compound
GO:0090280 positive regulation of calcium ion import
GO:1904783 positive regulation of NMDA glutamate receptor activity
GO:1905563 negative regulation of vascular endothelial cell proliferation
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
GO:2000353 positive regulation of endothelial cell apoptotic process
GO:2000427 positive regulation of apoptotic cell clearance
GO:2000502 negative regulation of natural killer cell chemotaxis

Diseases

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Interactions

78 interactions

InteractorPartnerSourcesPublicationsLink
CCL2RNF4BioGRID, IntAct32296183 details
CCL2TMX2BioGRID, IntAct32296183 details
CCL2CCL5bhf-ucl, BioGRID28381538 details
CCL2PF4bhf-ucl, BioGRID28381538 details
CCL2CCL15bhf-ucl, BioGRID28381538 details
CCL2CCL8bhf-ucl, BioGRID28381538 details
CCL2CCL11bhf-ucl, BioGRID28381538 details
CCL2CXCL8bhf-ucl, BioGRID28381538 details
CCL2CXCL9bhf-ucl, BioGRID28381538 details
CCL2CXCL17bhf-ucl, BioGRID28381538 details
CCL2CXCL13bhf-ucl28381538 details
CCL2CCL26bhf-ucl, BioGRID28381538 details
CCL2CCL4L1bhf-ucl, BioGRID28381538 details
CCL2CCL4L2bhf-ucl28381538 details
CCL2PROM1IntAct23084749 details
CCL2ACKR1BioGRID, HPRD13679391 17416748 details
CCL2CCL2BioGRID, HPRD7651403 8639605 8989326 details
CCL2CCR3BioGRID8642344 details
CCL2VCANBioGRID, HPRD11083865 details
CCL2SLC16A2BioGRID32296183 details
CCL2SLC22A1BioGRID31318583 details
CCL2SLC22A2BioGRID31318583 details
CCL2CCL13BioGRID28381538 details
CCL2XCL2BioGRID28381538 details
CCL2CDC6BioGRID21383955 details
CCL2ORC2BioGRID21383955 details
CCL2ORC4BioGRID21383955 details
CCL2MCM2BioGRID21383955 details
CCL2MCM3BioGRID21383955 details
CCL2MCM7BioGRID21383955 details
CCL2CDC45BioGRID21383955 details
CCL2PCNABioGRID21383955 details
CCL2MMP1HPRD12149192 9558113 details
CCL2MMP8HPRD12149192 9558113 details
CCL2MMP3HPRD12149192 9558113 details
CCL2CCR10HPRD10706668 9364936 details
CCL2CCR1HPRD8631787 details
CCL2CCR2HPRD10529171 9287323 details
CCL2CCR5HPRD10477718 details
CCL2ACKR4HPRD10734104 details
CCL2ACKR2HPRD9364936 9405404 details
CCL2SNAI1IntAct25314079 details
CCL2RELAIntAct20952659 24634218 details
CCL2MAFBIntAct22820162 details
CCL2H4-16IntAct22820162 details
CCL2H4C15IntAct22820162 details
CCL2H4C9IntAct22820162 details
CCL2H4C1IntAct22820162 details
CCL2H4C4IntAct22820162 details
CCL2H4C6IntAct22820162 details
CCL2H4C12IntAct22820162 details
CCL2H4C11IntAct22820162 details
CCL2H4C3IntAct22820162 details
CCL2H4C8IntAct22820162 details
CCL2H4C2IntAct22820162 details
CCL2H4C5IntAct22820162 details
CCL2H4C13IntAct22820162 details
CCL2H4C14IntAct22820162 details
CCL2KLF6IntAct24634218 details
CCL2PKNOX1IntAct21760952 details
CCL2HOXA9IntAct21760952 details
CCL2PBX2IntAct21760952 details
CCL2IRF1IntAct21760952 details
CCL2ZIC3IntAct33179750 details
CCL2ZIC1IntAct33179750 details
CCL2ZDHHC7IntAct33179750 details
CCL2SP4IntAct33179750 details
CCL2SOX14IntAct33179750 details
CCL2SMAD4IntAct33179750 details
CCL2GABPAIntAct33179750 details
CCL2ETV7IntAct33179750 details
CCL2ETV3IntAct33179750 details
CCL2ETV1IntAct33179750 details
CCL2ELK4IntAct33179750 details
CCL2ELK1IntAct33179750 details
CCL2ELF3IntAct33179750 details
CCL2ELF2IntAct33179750 details
CCL2DDX58BioGRID32513696 details