Entity Details

Primary name SELP
Entity type gene
Source Source Link

Details

PrimaryID6403
RefseqGeneNG_012125
SymbolSELP
Nameselectin P
Chromosome1
Location1q24.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsLYAM3_HUMAN

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0002576 platelet degranulation
GO:0002687 positive regulation of leukocyte migration
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 leukocyte cell-cell adhesion
GO:0008201 heparin binding
GO:0009897 external side of plasma membrane
GO:0010572 positive regulation of platelet activation
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0031088 platelet dense granule membrane
GO:0031092 platelet alpha granule membrane
GO:0032496 response to lipopolysaccharide
GO:0033623 regulation of integrin activation
GO:0033691 sialic acid binding
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042806 fucose binding
GO:0043208 glycosphingolipid binding
GO:0048306 calcium-dependent protein binding
GO:0050829 defense response to Gram-negative bacterium
GO:0050900 leukocyte migration
GO:0050901 leukocyte tethering or rolling
GO:0070492 oligosaccharide binding
GO:1903238 positive regulation of leukocyte tethering or rolling

Diseases

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Disease IDSourceNameDescription
601367 OMIMIschemic stroke (ISCHSTR)A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Interactions

11 interactions

InteractorPartnerSourcesPublicationsLink
SELPSELPLGBioGRID, DIP, HPIDb, IntAct10713099 11081633 19118202 26627825 details
SELPSNX17BioGRID, HPRD11237770 23382219 details
SELPCD24BioGRID, HPRD9129046 details
SELPGP1BABioGRID, HPRD10499919 details
SELPVCANBioGRID, HPRD10950950 details
SELPEZRBioGRID, HPRD10733515 details
SELPSNX27BioGRID23382219 details
SELPSERPING1BioGRID, HPRD14568956 details
SELPAP1M1BioGRID, HPRD11247301 details
SELPSELPHPRD11081633 details
SELPFUT4HPRD7508745 details