Entity Details

Primary name SLC5A1
Entity type gene
Source Source Link

Details

PrimaryID6523
RefseqGeneNG_017045
SymbolSLC5A1
Namesolute carrier family 5 member 1
Chromosome22
Location22q12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSC5A1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000017 alpha-glucoside transport
GO:0005354 galactose transmembrane transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0005367 myo-inositol:sodium symporter activity
GO:0005372 water transmembrane transporter activity
GO:0005412 glucose:sodium symporter activity
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006814 sodium ion transport
GO:0010035 response to inorganic substance
GO:0015146 pentose transmembrane transporter activity
GO:0015150 fucose transmembrane transporter activity
GO:0015151 alpha-glucoside transmembrane transporter activity
GO:0015750 pentose transmembrane transport
GO:0015756 fucose transmembrane transport
GO:0015757 galactose transmembrane transport
GO:0015798 myo-inositol transport
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0031526 brush border membrane
GO:0035377 transepithelial water transport
GO:0043229 intracellular organelle
GO:0048471 perinuclear region of cytoplasm
GO:0055056 D-glucose transmembrane transporter activity
GO:0070062 extracellular exosome
GO:0097708 intracellular vesicle
GO:0098708 glucose import across plasma membrane
GO:0098719 sodium ion import across plasma membrane
GO:0106001 intestinal hexose absorption
GO:0150104 transport across blood-brain barrier
GO:1904659 glucose transmembrane transport

Diseases

Show/Hide Table
Disease IDSourceNameDescription
606824 OMIMCongenital glucose/galactose malabsorption (GGM)Intestinal monosaccharide transporter deficiency. It is an autosomal recessive disorder manifesting itself within the first weeks of life. It is characterized by severe diarrhea and dehydration which are usually fatal unless glucose and galactose are eliminated from the diet. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SLC5A1EGFRIntAct18455122 details
SLC5A1PAWRBioGRID15090548 details
SLC5A1HSPA1ABioGRID, HPRD12082088 details
SLC5A1DDX58BioGRID32513696 details