Entity Details

Primary name SLC22A4
Entity type gene
Source Source Link

Details

PrimaryID6583
RefseqGeneNG_012129
SymbolSLC22A4
Namesolute carrier family 22 member 4
Chromosome5
Location5q31.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-16
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsS22A4_HUMAN

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006641 triglyceride metabolic process
GO:0006814 sodium ion transport
GO:0007589 body fluid secretion
GO:0008513 secondary active organic cation transmembrane transporter activity
GO:0009437 carnitine metabolic process
GO:0015171 amino acid transmembrane transporter activity
GO:0015226 carnitine transmembrane transporter activity
GO:0015293 symporter activity
GO:0015491 cation:cation antiporter activity
GO:0015651 quaternary ammonium group transmembrane transporter activity
GO:0015695 organic cation transport
GO:0015697 quaternary ammonium group transport
GO:0015879 carnitine transport
GO:0016324 apical plasma membrane
GO:0030165 PDZ domain binding
GO:0042908 xenobiotic transport
GO:0089718 amino acid import across plasma membrane

Diseases

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Disease IDSourceNameDescription
180300 OMIMRheumatoid arthritis (RA)An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Interactions

6 interactions