Entity Details

Primary name TAT
Entity type gene
Source Source Link

Details

PrimaryID6898
RefseqGeneNG_008235
SymbolTAT
Nametyrosine aminotransferase
Chromosome16
Location16q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-05-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsATTY_HUMAN

GO terms

Show/Hide Table
GOName
GO:0004838 L-tyrosine:2-oxoglutarate aminotransferase activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006103 2-oxoglutarate metabolic process
GO:0006536 glutamate metabolic process
GO:0006559 L-phenylalanine catabolic process
GO:0006572 tyrosine catabolic process
GO:0006979 response to oxidative stress
GO:0009058 biosynthetic process
GO:0016597 amino acid binding
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0046689 response to mercury ion
GO:0051384 response to glucocorticoid

Diseases

Show/Hide Table
Disease IDSourceNameDescription
276600 OMIMTyrosinemia 2 (TYRSN2)An inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, and oculocutaneous manifestations. Typical features include palmoplantar keratosis, painful corneal ulcers, and mental retardation. The disease is caused by variants affecting the gene represented in this entry.

Interactions

9 interactions