Entity Details

Primary name SLC52A2
Entity type gene
Source Source Link

Details

PrimaryID79581
RefseqGeneNG_032872
SymbolSLC52A2
Namesolute carrier family 52 member 2
Chromosome8
Location8q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-12
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsS52A2_HUMAN

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006771 riboflavin metabolic process
GO:0032217 riboflavin transmembrane transporter activity
GO:0032218 riboflavin transport
GO:0062124 4-hydroxybutyrate receptor activity

Diseases

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Disease IDSourceNameDescription
614707 OMIMBrown-Vialetto-Van Laere syndrome 2 (BVVLS2)An autosomal recessive progressive neurologic disorder characterized by early childhood onset of sensorineural deafness, bulbar dysfunction, and severe diffuse muscle weakness and wasting resulting in respiratory insufficiency and loss of independent ambulation. Because it results from a defect in riboflavin metabolism, some patients may benefit from high-dose riboflavin supplementation. The disease is caused by variants affecting the gene represented in this entry.

Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
SLC52A2CDC23BioGRID, IntAct25416956 details
SLC52A2FAM209ABioGRID, IntAct32296183 details
SLC52A2ADRB2BioGRID, MINT24561123 28298427 details
SLC52A2CHRM2BioGRID, MINT28298427 details
SLC52A2UPK1ABioGRID, IntAct28514442 details
SLC52A2SPPL2BBioGRID, IntAct28514442 details
SLC52A2TRIM25BioGRID29117863 details