Entity Details

Primary name ZNF750
Entity type gene
Source Source Link

Details

PrimaryID79755
RefseqGeneNG_011604
SymbolZNF750
Namezinc finger protein 750
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsZN750_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0008544 epidermis development
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0030154 cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:1990841 promoter-specific chromatin binding

Diseases

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Disease IDSourceNameDescription
610227 OMIMSeborrhea-like dermatitis with psoriasiform elements (SLDP)Characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ZNF750CTBP2BioGRID, IntAct25416956 details