Entity Details

Primary name KDM8
Entity type gene
Source Source Link

Details

PrimaryID79831
RefseqGene
SymbolKDM8
Namelysine demethylase 8
Chromosome16
Location16p12.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsKDM8_HUMAN

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0003682 chromatin binding
GO:0004175 endopeptidase activity
GO:0004177 aminopeptidase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0031648 protein destabilization
GO:0032922 circadian regulation of gene expression
GO:0035064 methylated histone binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0051864 histone demethylase activity (H3-K36 specific)
GO:0070544 histone H3-K36 demethylation
GO:0140554 L-arginine 3-hydroxylase activity

Diseases

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Interactions

19 interactions

InteractorPartnerSourcesPublicationsLink
KDM8PCYT2BioGRID, HPRD, IntAct16189514 details
KDM8NUBPLBioGRID, IntAct32296183 details
KDM8ISY1-RAB43IntAct32296183 details
KDM8ISY1BioGRID, IntAct32296183 details
KDM8DDIT4LBioGRID, IntAct32296183 details
KDM8IFT20BioGRID, IntAct32296183 details
KDM8PKMBioGRID24344305 details
KDM8MEOX2BioGRID26871637 32296183 details
KDM8H3C1BioGRID24981860 details
KDM8RCCD1BioGRID, IntAct, MINT24981860 28514442 details
KDM8CD70BioGRID, IntAct28514442 details
KDM8YJU2BBioGRID, IntAct26186194 28514442 details
KDM8UNC5CLBioGRID, IntAct28514442 details
KDM8HMGN1BioGRID, MINT24981860 details
KDM8HMGN2BioGRID, MINT24981860 details
KDM8EIF1ADBioGRID, MINT24981860 details
KDM8H2BC5BioGRID, MINT24981860 details
KDM8RNF123BioGRID29676528 details
KDM8KCTD10BioGRID31280863 details