Entity Details

Primary name NLRC5
Entity type gene
Source Source Link

Details

PrimaryID84166
RefseqGeneNG_030337
SymbolNLRC5
NameNLR family CARD domain containing 5
Chromosome16
Location16q13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-17
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsNLRC5_HUMAN

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0009617 response to bacterium
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032480 negative regulation of type I interferon production
GO:0035556 intracellular signal transduction
GO:0043549 regulation of kinase activity
GO:0045087 innate immune response
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051607 defense response to virus
GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0060340 positive regulation of type I interferon-mediated signaling pathway

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
NLRC5DDX58BioGRID20434986 details
NLRC5IFIH1BioGRID20434986 details
NLRC5CHUKBioGRID, IntAct20434986 details
NLRC5IKBKBBioGRID, IntAct20434986 details
NLRC5HNRNPLBioGRID28611215 details
NLRC5VIRMABioGRID29507755 details