Entity Details

Primary name HES7
Entity type gene
Source Source Link

Details

PrimaryID84667
RefseqGeneNG_015816
SymbolHES7
Namehes family bHLH transcription factor 7
Chromosome17
Location17p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-26
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHES7_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001756 somitogenesis
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007219 Notch signaling pathway
GO:0007498 mesoderm development
GO:0008134 transcription factor binding
GO:0009952 anterior/posterior pattern specification
GO:0036342 post-anal tail morphogenesis
GO:0046983 protein dimerization activity
GO:0048511 rhythmic process
GO:0050767 regulation of neurogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Disease IDSourceNameDescription
613686 OMIMSpondylocostal dysostosis 4, autosomal recessive (SCDO4)A rare condition of variable severity characterized by vertebral and costal anomalies. The main feature include dwarfism, vertebral fusion, hemivertebrae, posterior rib fusion, reduced rib number, and other rib malformations. The disease is caused by variants affecting the gene represented in this entry.

Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
HES7QARS1BioGRID, IntAct32296183 details
HES7PIH1D2BioGRID, IntAct32296183 details
HES7PRPF31BioGRID, IntAct32296183 details
HES7TCEANCBioGRID, IntAct32296183 details
HES7TCEA2BioGRID, IntAct32296183 details
HES7OSTF1BioGRID32296183 details
HES7H4C1BioGRID30804502 details
HES7HNRNPH1BioGRID26760575 details
HES7DDX58BioGRID32513696 details