Entity Details

Primary name ITGA8
Entity type gene
Source Source Link

Details

PrimaryID8516
RefseqGeneNG_034116
SymbolITGA8
Nameintegrin subunit alpha 8
Chromosome10
Location10p13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITA8_HUMAN

GO terms

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GOName
GO:0001822 kidney development
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007420 brain development
GO:0008305 integrin complex
GO:0009986 cell surface
GO:0014069 postsynaptic density
GO:0030198 extracellular matrix organization
GO:0032591 dendritic spine membrane
GO:0034446 substrate adhesion-dependent cell spreading
GO:0034678 integrin alpha8-beta1 complex
GO:0043204 perikaryon
GO:0046872 metal ion binding
GO:0048333 mesodermal cell differentiation
GO:0098609 cell-cell adhesion

Diseases

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Disease IDSourceNameDescription
191830 OMIMRenal hypodysplasia/aplasia 1 (RHDA1)A perinatally lethal renal disease encompassing a spectrum of kidney development defects, including renal agenesis, bilateral renal aplasia, hypoplasia, (cystic) dysplasia, and severe obstructive uropathy. The disease is caused by variants affecting the gene represented in this entry.