Entity Details

Primary name RABL3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5HYI8
EntryNameRABL3_HUMAN
FullNameRab-like protein 3
TaxID9606
Evidenceevidence at protein level
Length236
SequenceStatuscomplete
DateCreated2007-12-04
DateModified2021-06-02

Ontological Relatives

GenesRABL3

GO terms

Show/Hide Table
GOName
GO:0001779 natural killer cell differentiation
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0006886 intracellular protein transport
GO:0012505 endomembrane system
GO:0030183 B cell differentiation
GO:0033077 T cell differentiation in thymus
GO:0042803 protein homodimerization activity
GO:0046578 regulation of Ras protein signal transduction
GO:0050821 protein stabilization
GO:1903059 regulation of protein lipidation

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
618680 OMIMPancreatic cancer 5 (PNCA5)A malignant neoplasm of the pancreas. Tumors can arise from both the exocrine and endocrine portions of the pancreas, but 95% of them develop from the exocrine portion, including the ductal epithelium, acinar cells, connective tissue, and lymphatic tissue. Disease susceptibility is associated with variants affecting the gene represented in this entry. RABL3 variants have been found in families with a history of pancreatic ductal adenocarcinoma and multiple other occurrences of cancer, including melanoma, breast cancer, prostate cancer, and colon cancer.

Interactions

4 interactions