Entity Details

Primary name PGAP3
Entity type gene
Source Source Link

Details

PrimaryID93210
RefseqGeneNG_034125
SymbolPGAP3
Namepost-GPI attachment to proteins phospholipase 3
Chromosome17
Location17q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-07-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPGAP3_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0006505 GPI anchor metabolic process
GO:0006506 GPI anchor biosynthetic process
GO:0016021 integral component of membrane
GO:0016788 hydrolase activity, acting on ester bonds
GO:0031227 intrinsic component of endoplasmic reticulum membrane

Diseases

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Disease IDSourceNameDescription
615716 OMIMHyperphosphatasia with mental retardation syndrome 4 (HPMRS4)An autosomal recessive neurologic disorder characterized by profound developmental delay, severe mental retardation, no speech, psychomotor delay, postnatal microcephaly, and elevated serum alkaline phosphatase. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
PGAP3CREB3IntAct31515488 details
PGAP3GTF3C3IntAct32814053 details
PGAP3TBRG4BioGRID, IntAct26186194 28514442 details
PGAP3VKORC1L1BioGRID26186194 details
PGAP3RNF123BioGRID29676528 details