| Disease ID | Source | Name | Description |
| 609796 | OMIM | Peeling skin syndrome 2 (PSS2) | A non-inflammatory and localized form of peeling skin syndrome, a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis. In PSS2 patients, skin peeling is painless and strictly limited to the dorsa of the hands and feet. It is accompanied by painless erythema and spontaneous non-scarring healing. Ultrastructural and histological analysis shows a level of blistering high in the epidermis at the stratum granulosum-stratum corneum junction. The disease is caused by variants affecting the gene represented in this entry. |