Entity Details

Primary name LPIN2
Entity type gene
Source Source Link

Details

PrimaryID9663
RefseqGeneNG_007507
SymbolLPIN2
Namelipin 2
Chromosome18
Location18p11.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-01-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsLPIN2_HUMAN

GO terms

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GOName
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006629 lipid metabolic process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0008195 phosphatidate phosphatase activity
GO:0009062 fatty acid catabolic process
GO:0019432 triglyceride biosynthetic process
GO:0032869 cellular response to insulin stimulus
GO:0044255 cellular lipid metabolic process
GO:0045944 positive regulation of transcription by RNA polymerase II

Diseases

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Disease IDSourceNameDescription
609628 OMIMMajeed syndrome (MJDS)An autosomal recessive syndrome characterized by chronic recurrent multifocal osteomyelitis that is of early onset with a lifelong course, congenital dyserythropoietic anemia that presents as hypochromic, microcytic anemia during the first year of life and ranges from mild to transfusion-dependent, and transient inflammatory dermatosis, often manifesting as Sweet syndrome (neutrophilic skin infiltration). The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
LPIN2PPP1CABioGRID, IntAct22321011 details
LPIN2LPIN3BioGRID, IntAct28514442 details
LPIN2FBXW11BioGRID25332235 25515538 details
LPIN2VIRMABioGRID29507755 details