Entity Details

Primary name HERPUD1
Entity type gene
Source Source Link

Details

PrimaryID9709
RefseqGene
SymbolHERPUD1
Namehomocysteine inducible ER protein with ubiquitin like domain 1
Chromosome16
Location16q13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-11-29
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsHERP1_HUMAN

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006986 response to unfolded protein
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031396 regulation of protein ubiquitination
GO:0032469 endoplasmic reticulum calcium ion homeostasis
GO:0034976 response to endoplasmic reticulum stress
GO:0036499 PERK-mediated unfolded protein response
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044322 endoplasmic reticulum quality control compartment
GO:0044325 transmembrane transporter binding
GO:0045047 protein targeting to ER
GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1990037 Lewy body core
GO:1990756 ubiquitin ligase-substrate adaptor activity
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
HERPUD1CD58BioGRID, HPRD, IntAct16169070 details
HERPUD1RPA2BioGRID, HPRD, IntAct16169070 details
HERPUD1STARD9BioGRID, HPRD, IntAct16169070 details
HERPUD1IMPA2HPRD, IntAct16169070 details
HERPUD1EWSR1BioGRID, HPRD, IntAct16189514 details
HERPUD1USP7BioGRID, HPRD, IntAct16713569 details
HERPUD1TOLLIPBioGRID, IntAct20936779 details
HERPUD1ARHGDIABioGRID, MINT21900206 details
HERPUD1XRCC6BioGRID, MINT21900206 details
HERPUD1AMFRBioGRID, DIP17310145 19223579 21636303 21965653 24366945 24496447 25409783 26424800 details
HERPUD1C5AR2BioGRID, MINT28298427 details
HERPUD1CCR2BioGRID, MINT28298427 details
HERPUD1F2RL1BioGRID, MINT28298427 details
HERPUD1CHRM2BioGRID, MINT28298427 details
HERPUD1SYVN1BioGRID, UniProt16289116 21149444 23867461 26424800 26471130 28827405 31056421 32614325 32738194 details
HERPUD1VCPBioGRID16289116 details
HERPUD1APPBioGRID21832049 details
HERPUD1SH3RF1BioGRID17420289 details
HERPUD1UBXN6UniProt18656546 details
HERPUD1PSEN1BioGRID, HPRD11799129 14550564 details
HERPUD1UBQLN1BioGRID18307982 details
HERPUD1UBQLN2BioGRID, HPRD18307982 30442662 details
HERPUD1UBQLN4BioGRID18307982 details
HERPUD1DERL1BioGRID16289116 details
HERPUD1SELENOSBioGRID16289116 details
HERPUD1SNCABioGRID20604806 details
HERPUD1SNCAIPBioGRID20604806 details
HERPUD1SIAH1BioGRID20604806 details
HERPUD1PSMD2BioGRID21149444 details
HERPUD1UBCBioGRID14550564 details
HERPUD1IL1R1BioGRID20054003 details
HERPUD1IL23ABioGRID20054003 details
HERPUD1DERL2BioGRID23867461 details
HERPUD1TBK1BioGRID28954889 details
HERPUD1HTTBioGRID29430620 details
HERPUD1CD3DHPRD18307982 details
HERPUD1ATG9ABioGRID, IntAct28514442 details
HERPUD1CAPN15BioGRID, IntAct26186194 28514442 details
HERPUD1FAM8A1BioGRID, UniProt28827405 details
HERPUD1SEL1LBioGRID, UniProt28827405 details
HERPUD1RNF4BioGRID29180619 details
HERPUD1LMBR1LBioGRID31073040 details
HERPUD1CGRRF1BioGRID32614325 details
HERPUD1RPN1BioGRID34079125 details
HERPUD1TRIM25BioGRID29117863 details