Entity Details

Primary name PR15B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5SWA1
EntryNamePR15B_HUMAN
FullNameProtein phosphatase 1 regulatory subunit 15B
TaxID9606
Evidenceevidence at protein level
Length713
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000164 protein phosphatase type 1 complex
GO:0001933 negative regulation of protein phosphorylation
GO:0005783 endoplasmic reticulum
GO:0006983 ER overload response
GO:0019888 protein phosphatase regulator activity
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0034976 response to endoplasmic reticulum stress
GO:0042542 response to hydrogen peroxide
GO:0070262 peptidyl-serine dephosphorylation
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR019512 Protein phosphatase 1, regulatory subunit 15B, N-terminalDomainDomain
IPR019523 Protein phosphatase 1, regulatory subunit 15A/B, C-terminalDomainDomain

Diseases

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Disease IDSourceNameDescription
616817 OMIMMicrocephaly, short stature, and impaired glucose metabolism 2 (MSSGM2)A disease characterized by microcephaly, mental retardation, short stature, and disturbed glucose metabolism. The disease is caused by variants affecting the gene represented in this entry.