Entity Details

Primary name EMARD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T6L9
EntryNameEMARD_HUMAN
FullNameEndoplasmic reticulum membrane-associated RNA degradation protein
TaxID9606
Evidenceevidence at transcript level
Length678
SequenceStatuscomplete
DateCreated2007-07-24
DateModified2021-06-02

Ontological Relatives

GenesERMARD

GO terms

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GOName
GO:0005789 endoplasmic reticulum membrane
GO:0007275 multicellular organism development
GO:0016021 integral component of membrane

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR025209 Domain of unknown function DUF4209DomainDomain
IPR039635 Endoplasmic reticulum membrane-associated RNA degradation proteinFamilyFamily

Diseases

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Disease IDSourceNameDescription
615544 OMIMPeriventricular nodular heterotopia 6 (PVNH6)A form of periventricular nodular heterotopia, a disorder resulting from a defect in the pattern of neuronal migration in which ectopic collections of neurons lie along the lateral ventricles of the brain or just beneath, contiguously or in isolated patches. PVNH6 results in delayed psychomotor development, delayed speech, strabismus, and onset of seizures with hypsarrhythmia in early infancy. The disease is caused by variants affecting the gene represented in this entry.

Interactions

0 interactions

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