Entity Details

Primary name CLTR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y271
EntryNameCLTR1_HUMAN
FullNameCysteinyl leukotriene receptor 1
TaxID9606
Evidenceevidence at protein level
Length337
SequenceStatuscomplete
DateCreated2002-02-11
DateModified2021-06-02

Ontological Relatives

GenesCYSLTR1

GO terms

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GOName
GO:0001631 cysteinyl leukotriene receptor activity
GO:0002437 inflammatory response to antigenic stimulus
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004974 leukotriene receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006816 calcium ion transport
GO:0006935 chemotaxis
GO:0006952 defense response
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0008528 G protein-coupled peptide receptor activity
GO:0016020 membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR004071 Cysteinyl leukotriene receptorFamilyFamily
IPR013310 Cysteinyl leukotriene receptor 1FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00471 MontelukastDrugbanksmall molecule
DB00549 ZafirlukastDrugbanksmall molecule
DB00587 CinalukastDrugbanksmall molecule
DB00716 NedocromilDrugbanksmall molecule
DB01411 PranlukastDrugbanksmall molecule
DB08855 Leukotriene C4Drugbanksmall molecule
DB11858 Leukotriene D4Drugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CLTR1_HUMANCLTR2_HUMANBioGRID, IntAct17693579 21203429 details