Entity Details

Primary name SLC2A10
Entity type gene
Source Source Link

Details

PrimaryID81031
RefseqGeneNG_016284
SymbolSLC2A10
Namesolute carrier family 2 member 10
Chromosome20
Location20q13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-04-02
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGTR10_HUMAN

GO terms

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GOName
GO:0005351 carbohydrate:proton symporter activity
GO:0005886 plasma membrane
GO:0008645 hexose transmembrane transport
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0012505 endomembrane system
GO:0015757 galactose transmembrane transport
GO:0016021 integral component of membrane
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032683 negative regulation of connective tissue growth factor production
GO:0033300 dehydroascorbic acid transmembrane transporter activity
GO:0043588 skin development
GO:0045454 cell redox homeostasis
GO:0048471 perinuclear region of cytoplasm
GO:0055056 D-glucose transmembrane transporter activity
GO:0060392 negative regulation of SMAD protein signal transduction
GO:0060840 artery development
GO:0070837 dehydroascorbic acid transport
GO:0072498 embryonic skeletal joint development
GO:0098708 glucose import across plasma membrane
GO:0150104 transport across blood-brain barrier
GO:1902729 negative regulation of proteoglycan biosynthetic process
GO:1902730 positive regulation of proteoglycan biosynthetic process
GO:1903053 regulation of extracellular matrix organization
GO:1904659 glucose transmembrane transport
GO:2001045 negative regulation of integrin-mediated signaling pathway

Diseases

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Disease IDSourceNameDescription
208050 OMIMArterial tortuosity syndrome (ATORS)An autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SLC2A10ESR2BioGRID29509190 details