Entity Details

Primary name SARM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6SZW1
EntryNameSARM1_HUMAN
FullNameNAD(+) hydrolase SARM1
TaxID9606
Evidenceevidence at protein level
Length724
SequenceStatuscomplete
DateCreated2005-05-10
DateModified2021-06-02

Ontological Relatives

GenesSARM1

GO terms

Show/Hide Table
GOName
GO:0003953 NAD+ nucleosidase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005874 microtubule
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0009749 response to glucose
GO:0019677 NAD catabolic process
GO:0030154 cell differentiation
GO:0030424 axon
GO:0030425 dendrite
GO:0031315 extrinsic component of mitochondrial outer membrane
GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway
GO:0035591 signaling adaptor activity
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0045087 innate immune response
GO:0045202 synapse
GO:0048678 response to axon injury
GO:0048814 regulation of dendrite morphogenesis
GO:0050135 NAD(P)+ nucleosidase activity
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:1901214 regulation of neuron death
GO:1901216 positive regulation of neuron death

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell projection
Cytoplasm
Mitochondrion

Domains

Show/Hide Table
DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR001660 Sterile alpha motif domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR039184 Sterile alpha and TIR motif-containing protein 1FamilyFamily

Diseases

Show/Hide Table