Entity Details

Primary name PK1L2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z442
EntryNamePK1L2_HUMAN
FullNamePolycystic kidney disease protein 1-like 2
TaxID9606
Evidenceevidence at protein level
Length2459
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesPKD1L2

GO terms

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GOName
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030246 carbohydrate binding
GO:0050982 detection of mechanical stimulus

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000203 GPS motifDomainDomain
IPR000922 D-galactoside/L-rhamnose binding SUEL lectin domainDomainDomain
IPR001024 PLAT/LH2 domainDomainDomain
IPR001304 C-type lectin-likeDomainDomain
IPR002859 PKD/REJ-like domainDomainDomain
IPR003915 Polycystic kidney disease type 2 proteinFamilyFamily
IPR013122 Polycystin cation channel, PKD1/PKD2DomainDomain
IPR014010 REJ domainDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR036392 PLAT/LH2 domain superfamilyFamilyHomologous superfamily
IPR042060 Polycystin-1 like, PLAT/LH2 domainDomainDomain
IPR043159 D-galactoside/L-rhamnose binding SUEL lectin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PK1L2_HUMANMTR1A_HUMANBioGRID, IntAct26514267 details
PK1L2_HUMANSRPK2_HUMANBioGRID26167880 details