Entity Details

Primary name CTU1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z7A3
EntryNameCTU1_HUMAN
FullNameCytoplasmic tRNA 2-thiolation protein 1
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated2007-04-03
DateModified2021-06-02

Ontological Relatives

GenesCTU1

GO terms

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GOName
GO:0000049 tRNA binding
GO:0002098 tRNA wobble uridine modification
GO:0002143 tRNA wobble position uridine thiolation
GO:0002144 cytosolic tRNA wobble base thiouridylase complex
GO:0005829 cytosol
GO:0006400 tRNA modification
GO:0016779 nucleotidyltransferase activity
GO:0032447 protein urmylation
GO:0034227 tRNA thio-modification

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000541 Cytoplasmic tRNA 2-thiolation protein 1FamilyFamily
IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminalDomainDomain
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR032442 Cytoplasmic tRNA 2-thiolation protein 1, C-terminalDomainDomain
IPR035107 tRNA thiolation protein, TtcA/Ctu1 typeFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CTU1_HUMANURM1_HUMANBioGRID, DIP19017811 21209336 details
CTU1_HUMANHSP74_HUMANBioGRID19017811 details