Entity Details

Primary name NHRF4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86UT5
EntryNameNHRF4_HUMAN
FullNameNa(+)/H(+) exchange regulatory cofactor NHE-RF4
TaxID9606
Evidenceevidence at protein level
Length571
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesPDZD3

GO terms

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GOName
GO:0005829 cytosol
GO:0005903 brush border
GO:0006811 ion transport
GO:0006833 water transport
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0008022 protein C-terminus binding
GO:0008200 ion channel inhibitor activity
GO:0009636 response to toxic substance
GO:0010754 negative regulation of cGMP-mediated signaling
GO:0016324 apical plasma membrane
GO:0030251 guanylate cyclase inhibitor activity
GO:0043296 apical junction complex
GO:0043495 protein-membrane adaptor activity
GO:0045177 apical part of cell
GO:0072659 protein localization to plasma membrane
GO:1990381 ubiquitin-specific protease binding

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR001478 PDZ domainDomainDomain
IPR031200 Na(+)/H(+) exchange regulatory cofactor NHERF-4FamilyFamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR041489 PDZ domain 6DomainDomain

Diseases

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