Entity Details

Primary name ARHGP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86VW2
EntryNameARHGP_HUMAN
FullNameRho guanine nucleotide exchange factor 25
TaxID9606
Evidenceevidence at protein level
Length580
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesARHGEF25

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0035023 regulation of Rho protein signal transduction

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR030738 Rho guanine nucleotide exchange factor 25FamilyFamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions