Entity Details

Primary name NAL10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86W26
EntryNameNAL10_HUMAN
FullNameNACHT, LRR and PYD domains-containing protein 10
TaxID9606
Evidenceevidence at protein level
Length655
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesNLRP10

GO terms

Show/Hide Table
GOName
GO:0002250 adaptive immune response
GO:0002827 positive regulation of T-helper 1 type immune response
GO:0003924 GTPase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0016887 ATP hydrolysis activity
GO:0019897 extrinsic component of plasma membrane
GO:0032730 positive regulation of interleukin-1 alpha production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0045087 innate immune response
GO:0050729 positive regulation of inflammatory response
GO:0050829 defense response to Gram-negative bacterium
GO:0050832 defense response to fungus
GO:1900426 positive regulation of defense response to bacterium
GO:2000318 positive regulation of T-helper 17 type immune response

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR004020 DAPIN domainDomainDomain
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR041075 NOD2, winged helix domainDomainDomain

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NAL10_HUMANANDR_HUMANBioGRID19762545 details
NAL10_HUMANEGFR_HUMANBioGRID23956138 details