Entity Details

Primary name LONP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86WA8
EntryNameLONP2_HUMAN
FullNameLon protease homolog 2, peroxisomal
TaxID9606
Evidenceevidence at protein level
Length852
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesLONP2

GO terms

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GOName
GO:0002020 protease binding
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0006625 protein targeting to peroxisome
GO:0007031 peroxisome organization
GO:0008104 protein localization
GO:0008233 peptidase activity
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0016485 protein processing
GO:0016558 protein import into peroxisome matrix
GO:0019899 enzyme binding
GO:0031998 regulation of fatty acid beta-oxidation

Subcellular Location

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Subcellular Location
Peroxisome matrix

Domains

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DomainNameCategoryType
IPR003111 Lon, substrate-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR004815 Lon protease, bacterial/eukaryotic-typeFamilyFamily
IPR008268 Peptidase S16, active siteSiteActive site
IPR008269 Peptidase S16, Lon proteolytic domainDomainDomain
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroupFamilyHomologous superfamily
IPR015947 PUA-like superfamilyFamilyHomologous superfamily
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR027065 Lon proteaseFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR027501 Lon protease homologue 2, peroxisomalFamilyFamily

Diseases

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