Entity Details

Primary name KMT5C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86Y97
EntryNameKMT5C_HUMAN
FullNameHistone-lysine N-methyltransferase KMT5C
TaxID9606
Evidenceevidence at protein level
Length462
SequenceStatuscomplete
DateCreated2007-04-03
DateModified2021-06-02

Ontological Relatives

GenesKMT5C

GO terms

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GOName
GO:0000779 condensed chromosome, centromeric region
GO:0000792 heterochromatin
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005721 pericentric heterochromatin
GO:0006281 DNA repair
GO:0034772 histone H4-K20 dimethylation
GO:0034773 histone H4-K20 trimethylation
GO:0042393 histone binding
GO:0042799 histone methyltransferase activity (H4-K20 specific)
GO:0045830 positive regulation of isotype switching
GO:0046872 metal ion binding
GO:1904047 S-adenosyl-L-methionine binding
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR025790 Suv4-20 family, animalFamilyFamily
IPR039977 Histone-lysine N-methyltransferase Suv4-20/Set9FamilyFamily
IPR041938 Histone-lysine N-methyltransferase, N-terminal domainFamilyHomologous superfamily
IPR044425 KMT5C , SET domainDomainDomain

Diseases

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