Entity Details

Primary name HIPK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86Z02
EntryNameHIPK1_HUMAN
FullNameHomeodomain-interacting protein kinase 1
TaxID9606
Evidenceevidence at protein level
Length1210
SequenceStatuscomplete
DateCreated2003-08-29
DateModified2021-06-02

Ontological Relatives

GenesHIPK1

GO terms

Show/Hide Table
GOName
GO:0001654 eye development
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0007224 smoothened signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0009952 anterior/posterior pattern specification
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0010842 retina layer formation
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030182 neuron differentiation
GO:0034333 adherens junction assembly
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0045766 positive regulation of angiogenesis
GO:0048596 embryonic camera-type eye morphogenesis
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:0060216 definitive hemopoiesis
GO:0060235 lens induction in camera-type eye
GO:0061072 iris morphogenesis
GO:0072577 endothelial cell apoptotic process
GO:0097191 extrinsic apoptotic signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

Show/Hide Table