Entity Details

Primary name M4K3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IVH8
EntryNameM4K3_HUMAN
FullNameMitogen-activated protein kinase kinase kinase kinase 3
TaxID9606
Evidenceevidence at protein level
Length894
SequenceStatuscomplete
DateCreated2003-03-28
DateModified2021-06-02

Ontological Relatives

GenesMAP4K3

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0007254 JNK cascade
GO:0008349 MAP kinase kinase kinase kinase activity
GO:0009411 response to UV
GO:0034612 response to tumor necrosis factor
GO:0035556 intracellular signal transduction
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001180 Citron homology (CNH) domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR021160 Mitogen-activated protein (MAP) kinase kinase kinase kinaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule