Entity Details

Primary name SCN4B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWT1
EntryNameSCN4B_HUMAN
FullNameSodium channel subunit beta-4
TaxID9606
Evidenceevidence at protein level
Length228
SequenceStatuscomplete
DateCreated2005-01-04
DateModified2021-06-02

Ontological Relatives

GenesSCN4B

GO terms

Show/Hide Table
GOName
GO:0001518 voltage-gated sodium channel complex
GO:0005244 voltage-gated ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0006814 sodium ion transport
GO:0010765 positive regulation of sodium ion transport
GO:0014704 intercalated disc
GO:0017080 sodium channel regulator activity
GO:0031226 intrinsic component of plasma membrane
GO:0035725 sodium ion transmembrane transport
GO:0044325 transmembrane transporter binding
GO:0060048 cardiac muscle contraction
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 membrane depolarization during cardiac muscle cell action potential
GO:0086016 AV node cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:2000649 regulation of sodium ion transmembrane transporter activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000920 Myelin P0 protein-relatedFamilyFamily
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR044572 Sodium channel subunit beta-4FamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00243 RanolazineDrugbanksmall molecule
DB00313 Valproic acidDrugbanksmall molecule
DB00776 OxcarbazepineDrugbanksmall molecule
DB00907 CocaineDrugbanksmall molecule
DB00909 ZonisamideDrugbanksmall molecule
DB05541 BrivaracetamDrugbanksmall molecule
DB13269 Dichlorobenzyl alcoholDrugbanksmall molecule
DB13961 Fish oilDrugbankbiotech

Interactions

4 interactions