Entity Details

Primary name NLS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NA29
EntryNameNLS1_HUMAN
FullNameSodium-dependent lysophosphatidylcholine symporter 1
TaxID9606
Evidenceevidence at protein level
Length543
SequenceStatuscomplete
DateCreated2007-01-23
DateModified2021-06-02

Ontological Relatives

GenesMFSD2A

GO terms

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GOName
GO:0003406 retinal pigment epithelium development
GO:0005324 long-chain fatty acid transporter activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006656 phosphatidylcholine biosynthetic process
GO:0007420 brain development
GO:0008594 photoreceptor cell morphogenesis
GO:0008643 carbohydrate transport
GO:0009267 cellular response to starvation
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0015245 fatty acid transmembrane transporter activity
GO:0015293 symporter activity
GO:0015908 fatty acid transport
GO:0015909 long-chain fatty acid transport
GO:0016021 integral component of membrane
GO:0021766 hippocampus development
GO:0030307 positive regulation of cell growth
GO:0031999 negative regulation of fatty acid beta-oxidation
GO:0034379 very-low-density lipoprotein particle assembly
GO:0035633 maintenance of blood-brain barrier
GO:0035845 photoreceptor cell outer segment organization
GO:0040014 regulation of multicellular organism growth
GO:0045056 transcytosis
GO:0050773 regulation of dendrite development
GO:0050890 cognition
GO:0051977 lysophospholipid transport
GO:0051978 lysophospholipid:sodium symporter activity
GO:0060042 retina morphogenesis in camera-type eye
GO:0060856 establishment of blood-brain barrier
GO:0061744 motor behavior
GO:0071702 organic substance transport
GO:0097009 energy homeostasis
GO:0140329 lysophospholipid translocation
GO:0140348 lysophosphatidylcholine flippase activity
GO:0150011 regulation of neuron projection arborization
GO:0150104 transport across blood-brain barrier
GO:0150172 regulation of phosphatidylcholine metabolic process
GO:0150175 regulation of phosphatidylethanolamine metabolic process
GO:0150178 regulation of phosphatidylserine metabolic process
GO:1901480 oleate transmembrane transporter activity
GO:1990379 lipid transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily
IPR039672 Lactose permease-likeFamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NLS1_HUMANTM242_HUMANBioGRID, IntAct32296183 details
NLS1_HUMANADRB2_HUMANBioGRID, MINT28298427 details
NLS1_HUMANSYCY2_HUMANIntAct26853155 details