Entity Details

Primary name KDM1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NB78
EntryNameKDM1B_HUMAN
FullNameLysine-specific histone demethylase 1B
TaxID9606
Evidenceevidence at protein level
Length822
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesKDM1B

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000786 nucleosome
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006349 regulation of gene expression by genetic imprinting
GO:0007275 multicellular organism development
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016579 protein deubiquitination
GO:0030522 intracellular receptor signaling pathway
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific)
GO:0034720 histone H3-K4 demethylation
GO:0042393 histone binding
GO:0044030 regulation of DNA methylation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002937 Amine oxidaseDomainDomain
IPR007526 SWIRM domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR011124 Zinc finger, CW-typeDomainDomain
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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