Entity Details

Primary name TPC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NHX9
EntryNameTPC2_HUMAN
FullNameTwo pore calcium channel protein 2
TaxID9606
Evidenceevidence at protein level
Length752
SequenceStatuscomplete
DateCreated2007-02-06
DateModified2021-06-02

Ontological Relatives

GenesTPCN2

GO terms

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GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006939 smooth muscle contraction
GO:0007040 lysosome organization
GO:0010008 endosome membrane
GO:0010506 regulation of autophagy
GO:0016021 integral component of membrane
GO:0019065 receptor-mediated endocytosis of virus by host cell
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0034220 ion transmembrane transport
GO:0034765 regulation of ion transmembrane transport
GO:0042802 identical protein binding
GO:0072345 NAADP-sensitive calcium-release channel activity

Subcellular Location

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Subcellular Location
Lysosome membrane

Domains

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DomainNameCategoryType
IPR005821 Ion transport domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028798 Two pore calcium channel protein 2FamilyFamily

Diseases

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