Entity Details

Primary name HDAC7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WUI4
EntryNameHDAC7_HUMAN
FullNameHistone deacetylase 7
TaxID9606
Evidenceevidence at protein level
Length952
SequenceStatuscomplete
DateCreated2003-05-16
DateModified2021-06-02

Ontological Relatives

GenesHDAC7

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0005080 protein kinase C binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006476 protein deacetylation
GO:0019901 protein kinase binding
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032703 negative regulation of interleukin-2 production
GO:0033558 protein deacetylase activity
GO:0045668 negative regulation of osteoblast differentiation
GO:0046872 metal ion binding
GO:0071889 14-3-3 protein binding
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000286 Histone deacetylase familyFamilyFamily
IPR017320 Histone deacetylase class II, eukaryoticFamilyFamily
IPR023696 Ureohydrolase domain superfamilyFamilyHomologous superfamily
IPR023801 Histone deacetylase domainDomainDomain
IPR037138 Histone deacetylase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04297 Trichostatin ADrugbanksmall molecule
DB05015 BelinostatDrugbanksmall molecule
DB06603 PanobinostatDrugbanksmall molecule

Interactions

108 interactions

InteractorPartnerSourcesPublicationsLink
HDAC7_HUMANKPCD2_HUMANBioGRID, HPRD, MINT15623513 17962809 details
HDAC7_HUMANCACO2_HUMANBioGRID, IntAct, MINT21516116 25416956 31515488 32296183 details
HDAC7_HUMANGNMT_HUMANBioGRID, MINT21516116 details
HDAC7_HUMAN1433T_HUMANBioGRID, HPRD, IntAct15161933 16956611 16980613 17369396 23752268 28514442 details
HDAC7_HUMANNCOR2_HUMANBioGRID, HPRD, IntAct10640276 11466315 16956611 23752268 details
HDAC7_HUMANMEF2C_HUMANBioGRID, IntAct11279209 18463162 23752268 details
HDAC7_HUMANNCOR1_HUMANBioGRID, IntAct11466315 23752268 details
HDAC7_HUMANHDAC3_HUMANBioGRID, HPRD, IntAct11466315 23752268 details
HDAC7_HUMANEGFR_HUMANBioGRID, IntAct24658140 25402006 31980649 details
HDAC7_HUMANREL_HUMANBioGRID, IntAct25416956 32296183 details
HDAC7_HUMANRIPP1_HUMANBioGRID, IntAct25416956 32296183 details
HDAC7_HUMANSDCB1_HUMANMINT26787460 details
HDAC7_HUMANGG6L9_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANGBG12_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANARI5A_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANKLF16_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANBRWD1_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANANKMT_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANCENPQ_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANNDKM_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANESM1_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANACO11_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANCC036_HUMANIntAct32296183 details
HDAC7_HUMANPP16A_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANRAC1_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANCDC42_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANNRIP2_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANTIAF1_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANMIEN1_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANRRAS2_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANRAC2_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANDDT4L_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANKRBA2_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANLDB2_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANUBL3_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANMOT4_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANSOGA1_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANRAC3_HUMANBioGRID, IntAct32296183 details
HDAC7_HUMANKAT5_HUMANBioGRID, HPRD12551922 details
HDAC7_HUMANEDNRA_HUMANBioGRID11262386 details
HDAC7_HUMANBCL6_HUMANBioGRID11929873 details
HDAC7_HUMANZBT16_HUMANBioGRID, HPRD11929873 details
HDAC7_HUMANMARK3_HUMANBioGRID16980613 details
HDAC7_HUMANMARK2_HUMANBioGRID16980613 details
HDAC7_HUMANACTN4_HUMANBioGRID16980305 details
HDAC7_HUMANMEF2A_HUMANBioGRID16956611 16980305 20590529 22308472 details
HDAC7_HUMANUBC9_HUMANBioGRID18625722 details
HDAC7_HUMANCASP8_HUMANBioGRID18458084 details
HDAC7_HUMANPP2AA_HUMANBioGRID18339811 details
HDAC7_HUMANHDAC1_HUMANBioGRID11279209 details
HDAC7_HUMANHDAC2_HUMANBioGRID11279209 30737378 details
HDAC7_HUMANHDAC4_HUMANBioGRID11279209 details
HDAC7_HUMANHDAC5_HUMANBioGRID11279209 details
HDAC7_HUMANHDAC7_HUMANBioGRID11279209 23752268 details
HDAC7_HUMANRUNX2_HUMANBioGRID17997710 details
HDAC7_HUMANHIF1A_HUMANBioGRID15280364 21148070 details
HDAC7_HUMANYPEL3_HUMANBioGRID32296183 details
HDAC7_HUMANMEOX2_HUMANBioGRID32296183 details
HDAC7_HUMANPHC2_HUMANBioGRID32296183 details
HDAC7_HUMANSIN3A_HUMANHPRD10640276 details
HDAC7_HUMAN1433G_HUMANBioGRID, HPRD, IntAct, MINT15324660 17353931 23752268 28514442 details
HDAC7_HUMAN1433Z_HUMANBioGRID, IntAct, MINT15161933 20224040 23752268 28514442 details
HDAC7_HUMAN1433S_HUMANBioGRID, DIP, IntAct, MINT15778465 18339811 23752268 details
HDAC7_HUMAN1433F_HUMANBioGRID, IntAct17979178 20224040 23752268 26496610 28514442 details
HDAC7_HUMAN1433B_HUMANBioGRID, IntAct17369396 23752268 24255178 28514442 details
HDAC7_HUMAN1433E_HUMANBioGRID, IntAct17369396 17979178 20224040 23752268 details
HDAC7_HUMANKI13B_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANRTKN_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANTESK2_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANDEN1A_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANKSR1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANSPD2A_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANZN638_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANGGYF1_HUMANIntActunassigned1312 details
HDAC7_HUMANSRGP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANIF4E2_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANMAST3_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANSI1L1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANDCLK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANCBY1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANKCTD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANINP5E_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANZBT21_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANLIMA1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANLRFN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANPPM1H_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANMAGI1_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANCING_HUMANBioGRID, IntAct27173435 unassigned1312 details
HDAC7_HUMANFOXP3_HUMANBioGRID, DIP17360565 details
HDAC7_HUMANIKZF1_HUMANBioGRID12015313 details
HDAC7_HUMANIKZF3_HUMANBioGRID12015313 details
HDAC7_HUMANIKZF4_HUMANBioGRID12015313 details
HDAC7_HUMANCTNB1_HUMANBioGRID20224040 21836063 27684187 30691485 details
HDAC7_HUMANESR1_HUMANBioGRID19917725 details
HDAC7_HUMANFOXA1_HUMANBioGRID19917725 details
HDAC7_HUMANTTP_HUMANBioGRID19738286 details
HDAC7_HUMANKPCD1_HUMANBioGRID, HPRD15623513 15738054 19029091 details
HDAC7_HUMANANDR_HUMANBioGRID16860317 details
HDAC7_HUMANPML_HUMANBioGRID18463162 22155184 details
HDAC7_HUMANNR2E1_HUMANBioGRID17873065 details
HDAC7_HUMANKLF4_HUMANBioGRID17827213 details
HDAC7_HUMANBCORL_HUMANBioGRID17379597 details
HDAC7_HUMANMYPT1_HUMANBioGRID17369396 details
HDAC7_HUMANPP1B_HUMANBioGRID17369396 details
HDAC7_HUMANKDM5B_HUMANBioGRID17373667 details
HDAC7_HUMANEP300_HUMANBioGRID15280364 details
HDAC7_HUMANCCAR2_HUMANBioGRID32152128 details
HDAC7_HUMANPPARD_HUMANHPRD12970571 details