Entity Details

Primary name SOCS4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WXH5
EntryNameSOCS4_HUMAN
FullNameSuppressor of cytokine signaling 4
TaxID9606
Evidenceevidence at protein level
Length440
SequenceStatuscomplete
DateCreated2002-04-16
DateModified2021-06-02

Ontological Relatives

GenesSOCS4

GO terms

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GOName
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0016567 protein ubiquitination
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 intracellular signal transduction
GO:0040008 regulation of growth
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001496 SOCS box domainDomainDomain
IPR022252 SOCS4/SOCS5 domainDomainDomain
IPR028416 Suppressor of cytokine signalling 4FamilyFamily
IPR035864 SOCS4, SH2 domainDomainDomain
IPR036036 SOCS box-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR037342 SOCS4, SOCS box domainDomainDomain

Diseases

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