Entity Details

Primary name RIN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WYP3
EntryNameRIN2_HUMAN
FullNameRas and Rab interactor 2
TaxID9606
Evidenceevidence at protein level
Length895
SequenceStatuscomplete
DateCreated2003-02-01
DateModified2021-06-02

Ontological Relatives

GenesRIN2

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0006897 endocytosis
GO:0007264 small GTPase mediated signal transduction
GO:0010595 positive regulation of endothelial cell migration
GO:0030695 GTPase regulator activity
GO:0043547 positive regulation of GTPase activity
GO:1904906 positive regulation of endothelial cell-matrix adhesion via fibronectin
GO:2001214 positive regulation of vasculogenesis

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR003123 VPS9 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035868 Ras and Rab interactor 2, SH2 domainDomainDomain
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR037191 VPS9 domain superfamilyFamilyHomologous superfamily

Diseases

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