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Entity Details
Primary name
ELMO1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q92556
EntryName
ELMO1_HUMAN
FullName
Engulfment and cell motility protein 1
TaxID
9606
Evidence
evidence at protein level
Length
727
SequenceStatus
complete
DateCreated
1997-11-01
DateModified
2021-06-02
Ontological Relatives
Genes
ELMO1
GO terms
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GO
Name
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0006911
phagocytosis, engulfment
GO:0006915
apoptotic process
GO:0007015
actin filament organization
GO:0016020
membrane
GO:0016477
cell migration
GO:0016601
Rac protein signal transduction
GO:0017124
SH3 domain binding
GO:0030036
actin cytoskeleton organization
GO:0032045
guanyl-nucleotide exchange factor complex
GO:0038096
Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0048010
vascular endothelial growth factor receptor signaling pathway
GO:0048870
cell motility
GO:0050690
regulation of defense response to virus by virus
GO:0050790
regulation of catalytic activity
Subcellular Location
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Subcellular Location
Cell membrane
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR001849
Pleckstrin homology domain
Domain
Domain
IPR006816
ELMO domain
Domain
Domain
IPR011989
Armadillo-like helical
Family
Homologous superfamily
IPR011993
PH-like domain superfamily
Family
Homologous superfamily
IPR016024
Armadillo-type fold
Family
Homologous superfamily
IPR024574
Domain of unknown function DUF3361
Domain
Domain
IPR030715
Engulfment and cell motility protein 1
Family
Family
Diseases
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Drugs
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Interactions
18 interactions
Interactor
Partner
Sources
Publications
Link
ELMO1_HUMAN
HCK_HUMAN
BioGRID, HPRD, MINT
12029088
details
ELMO1_HUMAN
RHOG_HUMAN
BioGRID, HPRD, IntAct
12879077
21930703
details
ELMO1_HUMAN
DOCK1_HUMAN
BioGRID, HPRD, IntAct, MINT
11595183
12134158
15247908
15723800
16495483
18768751
20016009
20732417
21930703
26186194
26882976
28514442
details
ELMO1_HUMAN
ZN398_HUMAN
BioGRID, IntAct
25416956
26186194
28514442
31515488
details
ELMO1_HUMAN
TRI54_HUMAN
BioGRID, IntAct
25416956
details
ELMO1_HUMAN
DOCK5_HUMAN
BioGRID, IntAct
21930703
26186194
28514442
32203420
details
ELMO1_HUMAN
DOCK4_HUMAN
BioGRID, IntAct
21930703
26186194
28514442
details
ELMO1_HUMAN
DOCK3_HUMAN
BioGRID, IntAct
21930703
26186194
28514442
32203420
details
ELMO1_HUMAN
AGRB1_HUMAN
BioGRID, DIP
17960134
21930703
details
ELMO1_HUMAN
DOCK2_HUMAN
BioGRID, DIP
14737186
21930703
details
ELMO1_HUMAN
AGRB3_HUMAN
BioGRID
21930703
details
ELMO1_HUMAN
ARL4A_HUMAN
BioGRID
21930703
details
ELMO1_HUMAN
CDC27_HUMAN
BioGRID
26882976
details
ELMO1_HUMAN
APBB1_HUMAN
BioGRID
29615491
details
ELMO1_HUMAN
CASS4_HUMAN
IntAct
31413325
details
ELMO1_HUMAN
PGH2_HUMAN
BioGRID
20732417
details
ELMO1_HUMAN
ARHGG_HUMAN
BioGRID
26882976
details
ELMO1_HUMAN
FGD1_HUMAN
HPRD
12134158
details
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