Entity Details

Primary name RNF34_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ969K3
EntryNameRNF34_HUMAN
FullNameE3 ubiquitin-protein ligase RNF34
TaxID9606
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesRNF34

GO terms

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GOName
GO:0002039 p53 binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006915 apoptotic process
GO:0012505 endomembrane system
GO:0016567 protein ubiquitination
GO:0016604 nuclear body
GO:0016607 nuclear speck
GO:0031625 ubiquitin protein ligase binding
GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0070936 protein K48-linked ubiquitination
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1901797 negative regulation of signal transduction by p53 class mediator
GO:1901981 phosphatidylinositol phosphate binding
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000374 regulation of oxygen metabolic process
GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Endomembrane system
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR036361 SAP domain superfamilyFamilyHomologous superfamily

Diseases

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