Entity Details

Primary name S47A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96FL8
EntryNameS47A1_HUMAN
FullNameMultidrug and toxin extrusion protein 1
TaxID9606
Evidenceevidence at protein level
Length570
SequenceStatuscomplete
DateCreated2007-12-04
DateModified2021-06-02

Ontological Relatives

GenesSLC47A1

GO terms

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GOName
GO:0005886 plasma membrane
GO:0015179 L-amino acid transmembrane transporter activity
GO:0015297 antiporter activity
GO:0015695 organic cation transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0022857 transmembrane transporter activity
GO:0031982 vesicle
GO:0042887 amide transmembrane transporter activity
GO:0042908 xenobiotic transport
GO:0042910 xenobiotic transmembrane transporter activity
GO:0055085 transmembrane transport
GO:0061459 L-arginine transmembrane transporter activity
GO:0089718 amino acid import across plasma membrane
GO:0097638 L-arginine import across plasma membrane
GO:1902475 L-alpha-amino acid transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002528 Multi antimicrobial extrusion proteinFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00205 PyrimethamineDrugbanksmall molecule
DB00243 RanolazineDrugbanksmall molecule
DB00331 MetforminDrugbanksmall molecule
DB00440 TrimethoprimDrugbanksmall molecule
DB00501 CimetidineDrugbanksmall molecule
DB00536 GuanidineDrugbanksmall molecule
DB00537 CiprofloxacinDrugbanksmall molecule
DB00567 CephalexinDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB00877 SirolimusDrugbanksmall molecule
DB00879 EmtricitabineDrugbanksmall molecule
DB00927 FamotidineDrugbanksmall molecule
DB01004 GanciclovirDrugbanksmall molecule
DB01018 GuanfacineDrugbanksmall molecule
DB01030 TopotecanDrugbanksmall molecule
DB01035 ProcainamideDrugbanksmall molecule
DB01043 MemantineDrugbanksmall molecule
DB01137 LevofloxacinDrugbanksmall molecule
DB01195 FlecainideDrugbanksmall molecule
DB01203 NadololDrugbanksmall molecule
DB01333 CefradineDrugbanksmall molecule
DB04574 Estrone sulfateDrugbanksmall molecule
DB04948 LofexidineDrugbanksmall molecule
DB06137 TirbanibulinDrugbanksmall molecule
DB06608 TafenoquineSwissprotsmall molecule
DB08837 TetraethylammoniumDrugbanksmall molecule
DB08840 N-methylnicotinamideSwissprotsmall molecule
DB09241 Methylene blueDrugbanksmall molecule
DB09343 TipiracilDrugbanksmall molecule
DB11652 TucatinibDrugbanksmall molecule
DB11732 LasmiditanDrugbanksmall molecule
DB11753 RifamycinDrugbanksmall molecule
DB11757 IstradefyllineDrugbanksmall molecule
DB11791 CapmatinibDrugbanksmall molecule
DB11799 BictegravirDrugbanksmall molecule
DB11837 OsilodrostatDrugbanksmall molecule
DB11901 ApalutamideDrugbanksmall molecule
DB11978 GlasdegibDrugbanksmall molecule
DB12001 AbemaciclibDrugbanksmall molecule
DB12141 GilteritinibDrugbanksmall molecule
DB12267 BrigatinibDrugbanksmall molecule
DB12332 RucaparibDrugbanksmall molecule
DB12377 RelebactamDrugbanksmall molecule
DB12457 RimegepantDrugbanksmall molecule
DB12500 FedratinibDrugbanksmall molecule
DB12615 PlazomicinDrugbanksmall molecule
DB12887 TazemetostatDrugbanksmall molecule
DB12978 PexidartinibDrugbanksmall molecule
DB13946 Testosterone undecanoateDrugbanksmall molecule
DB14761 RemdesivirDrugbanksmall molecule
DB14840 RipretinibDrugbanksmall molecule
DB15102 PemigatinibDrugbanksmall molecule
DB15305 RisdiplamSwissprotsmall molecule
DB15685 SelpercatinibDrugbanksmall molecule
DB15822 PralsetinibDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
S47A1_HUMANFXYD6_HUMANBioGRID, IntAct32296183 details