Entity Details

Primary name PLPP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96GD0
EntryNamePLPP_HUMAN
FullNameChronophin
TaxID9606
Evidenceevidence at protein level
Length296
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesPDXP

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004721 phosphoprotein phosphatase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005911 cell-cell junction
GO:0006114 glycerol biosynthetic process
GO:0006470 protein dephosphorylation
GO:0006650 glycerophospholipid metabolic process
GO:0007088 regulation of mitotic nuclear division
GO:0016311 dephosphorylation
GO:0016791 phosphatase activity
GO:0030836 positive regulation of actin filament depolymerization
GO:0031072 heat shock protein binding
GO:0031247 actin rod assembly
GO:0031258 lamellipodium membrane
GO:0032361 pyridoxal phosphate catabolic process
GO:0032465 regulation of cytokinesis
GO:0032587 ruffle membrane
GO:0033883 pyridoxal phosphatase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0036425 D-phosphoserine phosphatase activity
GO:0042803 protein homodimerization activity
GO:0043136 glycerol-3-phosphatase activity
GO:0071318 cellular response to ATP

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR006349 2-phosphoglycolate phosphatase, eukaryoticFamilyFamily
IPR006357 HAD-superfamily hydrolase, subfamily IIAFamilyFamily
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00165 PyridoxineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PLPP_HUMANSTK11_HUMANBioGRID, MINT25640309 details
PLPP_HUMANARRB1_HUMANBioGRID17500066 details
PLPP_HUMANPLPP_HUMANHPRD14522954 details