Entity Details

Primary name MRP8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96J66
EntryNameMRP8_HUMAN
FullNameATP-binding cassette sub-family C member 11
TaxID9606
Evidenceevidence at protein level
Length1382
SequenceStatuscomplete
DateCreated2006-03-07
DateModified2021-06-02

Ontological Relatives

GenesABCC11

GO terms

Show/Hide Table
GOName
GO:0005524 ATP binding
GO:0005774 vacuolar membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008514 organic anion transmembrane transporter activity
GO:0008559 ABC-type xenobiotic transporter activity
GO:0015216 purine nucleotide transmembrane transporter activity
GO:0015431 ABC-type glutathione S-conjugate transporter activity
GO:0015432 ABC-type bile acid transporter activity
GO:0015711 organic anion transport
GO:0015721 bile acid and bile salt transport
GO:0015865 purine nucleotide transport
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042908 xenobiotic transport
GO:0055085 transmembrane transport
GO:0070062 extracellular exosome
GO:0071716 leukotriene transport

Subcellular Location

Show/Hide Table
Subcellular Location
Apical cell membrane
Cell membrane
Cytoplasmic vesicle membrane
Vacuole membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030251 ATP-binding cassette subfamily C member 11FamilyFamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00158 Folic acidDrugbanksmall molecule
DB00286 Conjugated estrogensDrugbanksmall molecule
DB00328 IndomethacinDrugbanksmall molecule
DB00563 MethotrexateDrugbanksmall molecule
DB01032 ProbenecidDrugbanksmall molecule
DB02527 Cyclic adenosine monophosphateDrugbanksmall molecule
DB04348 Taurocholic acidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink