Entity Details

Primary name CTSR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96P56
EntryNameCTSR2_HUMAN
FullNameCation channel sperm-associated protein 2
TaxID9606
Evidenceevidence at protein level
Length530
SequenceStatuscomplete
DateCreated2007-07-24
DateModified2021-06-02

Ontological Relatives

GenesCATSPER2

GO terms

Show/Hide Table
GOName
GO:0005227 calcium activated cation channel activity
GO:0005244 voltage-gated ion channel activity
GO:0005262 calcium channel activity
GO:0005886 plasma membrane
GO:0007275 multicellular organism development
GO:0009566 fertilization
GO:0030317 flagellated sperm motility
GO:0031514 motile cilium
GO:0032570 response to progesterone
GO:0034765 regulation of ion transmembrane transport
GO:0035036 sperm-egg recognition
GO:0036128 CatSper complex
GO:0048240 sperm capacitation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell projection

Domains

Show/Hide Table
DomainNameCategoryType
IPR005821 Ion transport domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028747 Cation channel sperm-associated protein 2FamilyFamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
611102 OMIMDeafness-infertility syndrome (DIS)Characterized by deafness and infertility and is caused by large contiguous gene deletions at 15q15.3 that removes both STRC and CATSPER2 genes. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CTSR2_HUMANCAC1I_HUMANIntAct16740636 details