Entity Details

Primary name TREF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PN7
EntryNameTREF1_HUMAN
FullNameTranscriptional-regulating factor 1
TaxID9606
Evidenceevidence at protein level
Length1200
SequenceStatuscomplete
DateCreated2005-09-13
DateModified2021-06-02

Ontological Relatives

GenesTRERF1

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0016575 histone deacetylation
GO:0030374 nuclear receptor coactivator activity
GO:0033142 progesterone receptor binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0050847 progesterone receptor signaling pathway
GO:0071393 cellular response to progesterone stimulus

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000949 ELM2 domainDomainDomain
IPR001005 SANT/Myb domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR017884 SANT domainDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
TREF1_HUMANERR3_HUMANBioGRID, IntAct32296183 details
TREF1_HUMANEP300_HUMANBioGRID, HPRD11349124 details
TREF1_HUMANCBP_HUMANBioGRID, HPRD11349124 details
TREF1_HUMANSTF1_HUMANBioGRID, HPRD12101186 details